Biomedical Imaging Technologies

This comprehensive track will highlight emerging state-of-the-art optical imaging methods for biological and medical applications presented by leading experts in the field and fostering valuable interactions.

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The pioneering Biomedical Imaging Technologies track offers an unparalleled opportunity to delve into the forefront of optical imaging for biology and medicine. Participate in thought-provoking discussions and connect with fellow researchers, clinicians, and industry professionals.

The session will cover:

• Fluorescence Microscopy: recent advances and unique applications of diverse fluorescence microscopy techniques such as multiphoton, light-sheet, widefield, confocal, super-resolution, and fluorescence lifetime microscopy.
• Adaptive Optics: development and application of adaptive optics techniques to optimize imaging performance by compensating for optical aberrations in living tissues, paving the way for enhanced high-resolution imaging capabilities.
• Photoacoustic and Photothermal Imaging: advances in combining ultrasound and laser-induced tissue heating (photoacoustic) or temperature-sensitive imaging modalities (photothermal) for high-resolution imaging of biological tissues.
• Diffuse Optical Tomography (DOT) & Optical Coherence Tomography (OCT): development and applications of DOT and OCT for advanced studies of tissue chromophore concentrations, brain function, microstructure, morphology, etc.
• Holography: advances in digital holography for 3D imaging, with applications spanning microscopy, endoscopy, and ophthalmology.
• Spectroscopic Techniques: advances and applications of spectroscopic imaging techniques for biology and medicine, such as label-free chemical imaging with Raman spectroscopy/microscopy and tissue mechanical property measurement using Brillouin techniques.

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Invited Speaker

New generations of laser sources, with high pulse energy, wide continuous tunable range, and a compact form, are in high demand to advance two-photon and three-photon microscopy to its full potential for deep-tissue imaging.  Multimode fibers have emerged as an early-stage but promising candidate. Effective control of nonlinear processes at high power levels in multimode fibers (MMFs) would unlock new possibilities for diverse applications including high-power fiber lasers, which potentially address the aforementioned need. This talk will discuss our recently developed approach that exploits the spatial and temporal degrees of control of nonlinear effects in step-index MMFs using a 3D-printed programmable fiber piano. By leveraging the rich spatiotemporal degrees of freedom and the high spectral brilliance in SI MMF, We have achieved broadband high-peak-power spanning nm, resulting from combined spectral energy reallocation and temporal shortening uniquely enabled by the fiber shaper. Its potential as a nonlinear imaging source is further demonstrated by applying the MMF source to multiphoton microscopy, where multi-fold signal enhancement is achieved for label-free tissue imaging with adaptive optimization.

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Contributed Speakers

Omir Haim, The Hebrew University of Jerusalem, Israel, “Image-guided Computational Holographic Wavefront Shaping.”

Mojtaba Moghaddasi, Beijing Institute of Technology, China, “Compact, Wide-Angle, Nano-Optic Camera for Capsule Endoscopy.”

Maria Leonor Ribeiro, International Iberian Nanotechnology Laboratory, Portugal, “Metabolic Imaging of 2D and 3D live cell models using sub-10 fs ultra-broadband laser pulses.”

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Organizing Committee

Chair:

Fei Xia, The Kastler-Brossel Laboratory, École Normale Supérieure, France

Committee:

Bo Li, Fudan University, China
Chaohao Chen, The Australian National University, Australia
Vicente Parot, Catholic University of Chile, Chile
Najva Akbari, Stanford University, United States